Research labBengaluru CampusNargund Formulation & Nanotechnology Research Lab
The facility is developed to produce cutting-edge technology in formulation development of solid orals, liquid orals, ointments and creams for India, RoW, MENA, Australia, EU and USA markets.
At Nargund College of Pharmacy, Bengaluru.
- Key instruments
- 16
- Stability chambers
- 3
- Target markets
- 6
What we do
Formulation development, nano-formulations, pre-clinical studies and stability testing for the pharmaceutical industry.
- Formulation development and evaluation of solid oral, topical and liquid oral delivery systems.
- Pre-clinical animal studies of synthetic investigational drugs, and of herbal extracts for functionality tests.
- Quantitative estimation of herbal extracts, analytical method development and CoA generation.
- Troubleshooting for the pharma industry: product and production issues faced during manufacturing.
- Nano-formulations that increase bioavailability and deliver more efficient formulations.
- Stability studies of formulations developed by other organisations, with a submitted report.
Facilities available
- Nano-formulation development
- Solid orals development
- Topical dosage forms development
- Liquid orals development
- Synthesis of new drugs & evaluation
- Pre-clinical studies of new drugs or herbal extracts
- Quantitative analysis of herbal extracts or formulations
Formulation development facility
Solid orals, liquids, ointments and creams
Pilot-scale equipment that takes a formulation from blending and granulation through to compression and coating.
Mini tablet press
GMP model, Mini Press I (PT-D+B-10)
A high-speed 10-station press that compresses granules from wet granulation, dry granulation or direct compression into tablets with extreme precision.
- Max. tablet diameter 23 mm
- Max. depth of fill 18 mm
- Turret 10–30 rpm
- Punch length 133.65 mm
- Max. operating pressure 6 tons
Fluid bed dryer (FBD)
PFBD-2 Kg
The most widely used technique for drying pharmaceutical powders and granules, with direct contact between particles and air or gas.
- Container volume 2 litres
- Drying temperature 35–80 °C
- Motor 2 HP / 1.5 kW
- Inlet air filter 20 micron
Rapid mixer granulator (RMG)
A multipurpose processor for high-speed dispersion of dry powders, aqueous or solvent granulation, effervescent products and melt pelletisation.
- Gross capacity 3 litres (1 kg bowl)
- Max. working volume 0.5 kg
- Chopper blade 15–150 rpm
- Chopper motor 0.5 HP, 300 rpm
Double cone blender
Widely used for batch production and small quantities of powder, and efficient at mixing powders of different densities.
- Rotation 30–100 rpm
- Capacity 2 kg
Mini multimill
High-speed pulverising, mixing, shredding and chopping for wet and dry granulation, without special attachments.
- SS wire mesh sieve 5–20 mm
- Rotor 750 / 1500 / 2300 / 3000 rpm
Vibro sifter
6" model
A vibratory sifting system for sorting, scalping and grading in medicinal, chemical and food applications.
- Screen size 200 mm
Conventional coating pan
For sugar coating tablets and pills, and for film coating with a single spray polymer after compression.
- Loading capacity 2 kg
- Pan diameter 6 inch
- 1–24 rpm
Nano formulation development facility
Characterisation and cell studies at the nanoscale
Instruments for preparing, sizing and evaluating nano-formulations, including cell culture and live cell imaging.
Brookfield viscometer
Used to prepare homogeneous solutions, nano-emulsions and nano-suspensions.
- Speed 33,000 rpm
- Sample size 10 ml and above
BioSpectrometer
Eppendorf
Used for protein estimation and fluorescence estimation studies.
- Sample size 10 µl and above
- Wavelength 200–830 nm
Nanoparticle size analyser
Horiba SZ-100
Measures particle size, zeta potential and molecular weight of nano-formulations.
- Particle size 0.3 nm to 8 µm
- Zeta potential −200 to +200 mV
- Molecular weight 1 × 10³ to 2 × 10⁷ g/mol
Refrigerated centrifuge
Eppendorf 5430 R
High-speed, temperature-controlled centrifugation.
- Speed 30,134 × g
- Temperature −11 °C to 40 °C
Lyophiliser
Biobase
Freeze drying with a large sample space and quick drying.
- Cooling down to −60 °C
- High-pressure vacuum pump
Class II biosafety cabinet
Alpha Liner
Laminar air flow with a wide work space, for aseptic work.
- UV and white light
CO₂ incubator
Eppendorf Galaxy 170 S
Fanless, six-sided direct heating with low gas consumption and high-temperature disinfection.
- 170 L capacity
- Split, sealed inner glass doors
- IR CO₂ sensor
- RS-232 port, 25 mm access ports
Automated cell counter
Countess
Automated counting of cells for cell-culture studies.
Fluorescence microscope
EVOS FL Auto
Live cell imaging and area scanning, with image stitching and time-lapse imaging.
Evaluation
In-vitro and in-vivo testing
In-vitro evaluation
- In-vitro dissolution test apparatus
- Disintegration test apparatus
- Fick's diffusion cell
- Friability test apparatus
- Density tester
- Sieve shaker
- UV-visible spectroscopy
- FTIR spectroscopy
- HPLC
- Karl Fischer titrator
- Gas chromatography
In-vivo evaluation
- Animal house facility
- Electrophoresis
- Gel documentation system
- −60 °C deep freezer
- Single and double unit organ bath
- Analgesiometer
- Bio auto-analyser (urine and blood)
- Electroconvulsiometer
- Actophotometer
- Rotarod apparatus
- Plethysmometer
- Anti-anxiety study
- Eddy's hot plate
Stability studies
Shelf-life testing under controlled conditions
Our stability chambers are used extensively to test and evaluate the shelf life of formulations developed at the lab. We also take up stability studies of formulations developed by other organisations and submit the report.
25 °C / 60% RH
600 L chamber
30 °C / 75% RH
430 L chamber
40 °C / 75% RH
430 L chamber
Contact
Talk to the research lab
Formulation Development & Nanotechnology Research LabNargund College of Pharmacy, 2nd Main, Dattatreya Nagar, Hosakerehalli, Banashankari 3rd Stage, near 100 Ft Ring Road, Bengaluru 560085Get directions
www.nargund.edu.in